Before beginning any prescription drug regimen, you should be fully informed about the medicine and what it can do. Research the possible side effects, interactions, and any other important information before beginning treatment.

And, of course, you should only take prescription medications as prescribed and recommended to you by a qualified physician.

If you have been prescribed the drug Cortef, you may have a lot of questions before starting to take this drug regularly. If so, you’ve come to the right place.

In this guide, we will go over everything you need to know in order to use Cortef safely.

Uses of Cortef

The generic name of Cortef is hydrocortisone. It is considered a steroid because it prevents the release of substances in the body that cause inflammation.

Hydrocortisone can be used to treat many different conditions. These include allergies, arthritis, lupus, psoriasis, and many skin conditions.

It can also be used to treat some breathing disorders, like asthma. Disorders of the blood and immune system may also be treated with Cortef.

Hydrocortisone is a natural hormone that is produced by the adrenal gland in the body. It works by lessening your immune system’s response to diseases and other inflammatory conditions.

This, in turn, reduces the unpleasant symptoms like pain, swelling, and allergy-like reactions.

Possible Side Effects

You should be fully informed about the potential side effects of Cortef before beginning treatment.

Though there are some unpleasant possible side effects, you should keep in mind that if you have been prescribed this medication, it is because your doctor believes that the benefits to you will outweigh the potential side effects you may experience.

Many people do not experience any serious side effects.

Common Side Effects

Some of the common and relatively mild side effects of this drug include headaches, nausea, dizziness, heartburn, and difficulty sleeping. Women may experience changes in their menstrual cycle.

It can also affect your skin in the form of increased sweating and even acne.

Diabetes and Infections

This medication works by weakening the immune system. Because of this, your ability to fight infections may be altered.

You are at a greater risk of infections. If you have any signs of infection, you should tell your doctor right away.

In addition, those who have diabetes should be aware of the potential side effects as well.

The medication can make your blood sugar rise, which can worsen an existing case of diabetes or even bring it on. Increased thirst or urination are common symptoms of high blood sugar, and thus should be reported to your doctor.

More Serious Side Effects

These side effects are much less common, even rare. However, they are serious and should be reported to your doctor right away.

Unusual weight gain or tiredness, problems with your vision, easy bruising, general swelling, mood changes, pain or weakness, and thinning skin or slower wound healing are all very serious issues that could result from taking this medication.

In addition, this drug may cause serious (but seldom fatal) internal bleeding. This is very rare, but if you notice blood in your stools or persistent stomach pain, you should tell your doctor.

Chest pain and seizures are also reason to seek medical attention immediately. Symptoms of a serious allergic reaction like a rash, itching, trouble breathing, or severe dizziness are also cause for alarm.

Talk to Your Doctor

And, of course, just because something is not included in this list does not automatically mean it is not a side effect of the drug you are taking.

If you notice other symptoms that are not a noted side effect of the drug, you should still report them to your doctor or pharmacist immediately.

Taking Cortef Safely

There are some important elements to the proper usage of this drug. To take it safely, here are our recommendations.

Use Instructions

Cortef is taken orally. You should take it by mouth and it should not be taken alone or on an empty stomach.

Always take this medication with food or milk to help prevent an upset stomach. You should also take it with a full glass of water so that it dissolves properly and you stay hydrated.

Of course, all of this is subject to your doctor’s specific recommendations.

Take this medicine exactly as directed by your doctor, and talk to him or her if you have any questions or if you feel that something you read online is different from what they have advised you to do.

Follow the Dosing Schedule and Instructions

Another important part of taking this medication safely is to follow the dosing schedule exactly.

Your doctor will prescribe the proper dosage and adequate length of treatment to you depending on your specific situation.

Your condition and your body’s response to the treatment should both be taken into account when deciding the proper dosage for you.

Drug Interactions

Cortef has the potential to interact with other drugs. This can change how they work and increase your risk of more serious side effects.

Aldesleukin, mifepristone, and drugs that can cause bleeding or bruising (such as ibuprofen, naproxen, or blood thinners) all have the potential to interact with this medication.

Aspirin can also increase your risk of bleeding when used in combination with this medication.

This drug can also interfere with skin tests and other lab tests to create inaccurate test results.

Talk to Your Doctor Before Stopping Use

As with any drug, you should never discontinue use without first consulting your doctor. If this medication is suddenly stopped, some conditions have the potential to become worse.

In addition, there is a chance you could have withdrawal symptoms from a sudden stop. These symptoms could include weight loss, nausea, headaches, pain, weight loss, and dizziness.

Talk to your doctor right away if you ever feel ill or unwell during your use of this drug.

Instead, if you and your doctor make the decision together to cease your use of the drug, your dosage may need to be decreased gradually, over time.


If you have questions about Cortef or any other prescription drugs, feel free to browse around our website for more information.

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