Seasonique are birth control pills that consist of two hormones, progestin and estrogen. The pills are taken for 91 consecutive days, which means that women who take Seasonique get their periods only 4 times a year.

The hormones in Seasonique prevent pregnancy by preventing the release of an egg from the ovaries and changing the thickness of vaginal fluid so that sperm is unable to fertilize the egg, and changing the uterine lining so that a fertilized egg cannot attach.

In addition to preventing pregnancy, Seasonique birth control pills are often prescribed to regulate a woman’s menstrual cycle, reduce heavy blood loss and painful periods, limit symptoms of PMS, treat acne and decrease the risk of ovarian cysts.

Read on to find out more about how to take Seasonique, its side effects and much more.

How to Take Seasonique

It is very important that Seasonique is taken at the exact same time every day. Do not skip a dose. Pick a time of the day that is convenient and easy to remember, or set a reminder on your phone.

A good time to take it is after dinner or at bedtime, which may help if you experience nausea or stomach upset from the medication.

Begin taking the medication on the first Sunday after the start of your period. If your cycle starts on a Sunday, take it that same day.

The Seasonique pill pack contains 91 pills total, 84 light blue-green combination pills with estrogen and progestin, and 7 yellow pills with just estrogen.

Take one combination pill daily, at the same time each day, for 84 days. Then take one estrogen-only pill for 7 consecutive days. Your period should occur while taking the estrogen-only pills.

Begin a new pack on the day immediately after finishing a pack.

Seasonique Side Effects

Although Seasonique prevents pregnancy and treats heavy and painful periods, it does come with its side effects. Women may experience some, none or all of these when taking the medication.

These side effects include:

  • Nausea
  • Vomiting
  • Headaches
  • Bloating
  • Breast tenderness
  • Fluid retention
  • Weight change
  • Spotting between periods
  • Increased blood pressure
  • Blotchy, dark patches on your skin

If you do not get your period during the week you are taking the estrogen-only pill, consult your doctor. You should take a pregnancy test to rule out possible pregnancy.

Serious side effects might include:

  • Lumps in the breast
  • Depression
  • Abdominal pain
  • Unusual changes in vaginal bleeding
  • Dark urine
  • Jaundice

Consult your doctor right away if you experience any of these serious side effects.

Rare side effects include:

  • Blood clots
  • Chest pain
  • Confusion
  • Dizziness and fainting
  • Slurred speech
  • Shortness of breath
  • Headaches accompanied by blurred vision
  • Weakness on one side of the body

If you experience any of these rare side effects, seek medical attention right away.

Occasionally a person will experience a serious allergic reaction to Seasonique. A serious allergic reaction may include:

  • Rash
  • Swelling of the face, tongue or throat
  • Severe dizziness
  • Difficulty breathing

Seek medical help immediately if you experience a serious allergic reaction.

This is not a complete list. Consult your doctor if you are experiencing any other side effects not listed.


Do not take Seasonique if you are allergic to medications containing estrogen or progestin. You should also let your doctor know if you have a history of blood clots, high blood pressure, depression, diabetes or any other serious medical condition.

If you do become pregnant, stop taking Seasonique.

Consult your doctor about taking Seasonique if you are breastfeeding. It may reduce the production of breast milk. A small amount of the medication passes into breast milk and may cause side effects for your nursing baby.

Tell your doctor and pharmacist about any other medication you are taking, to make sure there are no adverse drug interactions.

Seasonique Medication Guide

The information provided is not complete. Please consult the insert that comes with the medication for a complete guide in regard to side effects, complications, precautions and overdose.

For more information about purchasing Seasonique online, click here.